The Henry McFarland NAIMS Workshop 2027

Molecular PET Imaging in Multiple Sclerosis, From Disease Mechanisms to Clinical Translation

March 10, 2027
Sheraton Phoenix Downtown
Phoenix, Arizona

The Henry McFarland NAIMS Workshop 2027 will be taking place Wednesday, March 10 from 8:30 am - 6:30 pm at the Sheraton Phoenix Downtown in Phoenix, Arizona. The workshop will be held ahead of the ACTRIMS Forum 2027, taking place March 11-13 2027.

Registration Fees
Delegate: professional employed by academic institution, hospital, government agency, or non-profit organization. $100
Young Investigator: student/trainee OR professional who has obtained an advanced degree (M.D. or Ph.D.) within seven years (2020 or later) of the time of the Forum. Proof is required. $50
Industry Representative: Professional who holds a non-research position and is employed by a pharmaceutical company or commercial entity. $150

2027 Workshop Planning Committee

Matthew Brier

Washington University in St. Louis

Korhan Buyukturkoglu

Columbia University

Richard Dortch

Barrow Neurological Institute

Leorah Freeman

Dell Medical School, The University of Texas at Austin

Susan Gauthier

Weill Cornell Medical College

Charles Guttman

Brigham and Women's Hospital

Dejan Jakimovski

Buffalo Neuroimaging Analysis Center, University at Buffalo, Neurology Department

Ajay Kumar

University of Pennsylvania

Caterina Mainero

Massachusetts General Hospital

Sridar Narayanan

McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University

Bart Rypma

University of Texas at Dallas

Burcu Zeydan

Mayo Clinic

Our Partners

If you’re interested in sponsorship opportunities, please refer to our sponsorship prospectus for more information.

Workshop Agenda

The Henry McFarland NAIMS Workshop 2027 will take place Wednesday, March 10, 2027. All times are listed in Mountain Standard Time (MST). This schedule is subject to change.

7:30 - 8:30 am
Breakfast
8:30 - 8:40 am
Welcome and Workshop Goals
Speaker: TBD
8:40 - 9:00 am
What Has PET Done for Us? Pathology and Molecular Imaging in MS
Laura Airas (University of Turku)
9:00 - 10:35 am
SESSION 1: Molecular Targets and the Tracers That Reach Them
Moderators: Matthew Brier (chair); Sridar Narayanan
  • 9:00 - 9:20 am: Imaging Inflammation: TSPO Across Its Generations, and What Lies Beyond — Burcu Zeydan (Mayo Clinic)
  • 9:20 - 9:40 am: Imaging Myelin: Tracers for Demyelination and Repair — Pedro Brugarolas (Massachusetts General Hospital)
  • 9:40 - 10:00 am: Imaging Neurodegeneration: Synaptic and Neuronal Targets Borrowed From Other Diseases — David Matuskey (Yale)
  • 10:00 - 10:20 am: Imaging Metabolic Stress: Glucose, Oxidative Injury, and Hypoxia
10:20 - 10:35 am — Panel Discussion
10:35 - 10:50 am
Break
10:50 - 11:45 am
SESSION 2: Quantification and Technology: Making the PET Measurement Trustworthy
Moderators: Burcu Zeydan (chair); Korhan Buyukturkoglu
  • 10:50 - 11:10 am: Quantifying the Signal: AI-Assisted Analysis and PET-MRI Integration — Julie Price (Massachusetts General Hospital)
  • 11:10 - 11:30 am: Acquiring the Signal: Integrated MR-PET, Digital Detectors, and Total-Body Systems — Georges El Fakhri (Yale)
11:30 - 11:45 am — Panel Discussion
11:45 am - 12:30 pm
Lunch
12:30 - 1:45 pm
SESSION 3: Biological Insight: What PET Reveals About MS Pathology
Moderators: Caterina Mainero (chair); Ajay Kumar
  • 12:30 - 12:50 pm: Inflammation in the White Matter: Chronic Active Lesions and the Normal-Appearing Brain — Susan Gauthier (Weill Cornell Medicine)
  • 12:50 - 1:10 pm: Inflammation in the Gray Matter and at the Brain's Borders: Cortex, Meninges, and Choroid Plexus — Caterina Mainero (Massachusetts General Hospital)
  • 1:10 - 1:30 pm: Beyond Inflammation: Tissue Injury, Repair, and Neurodegeneration — Bruno Stankoff (Paris Brain Institute)
1:30 - 1:45 pm — Panel Discussion
1:45 - 1:55 pm
Break
1:55 - 3:10 pm
SESSION 4: Clinical Translation: PET as a Trial Endpoint and a Clinical Tool
Moderators: Susan Gauthier (chair); Leorah Freeman
  • 1:55 - 2:15 pm: TSPO PET as a Phase II Endpoint: Feasibility, Population, and Target Tissue — Matthew Brier (Washington University in St. Louis)
  • 2:15 - 2:35 pm: Myelin PET in Remyelination Trials: Advantages Over and Alongside MRI — Benedetta Bodini (Paris Brain Institute)
  • 2:35 - 2:55 pm: Lessons From Alzheimer's Disease: How PET Became a Multisite Endpoint — Susan Landau (UC Berkley)
2:55 - 3:10 pm — Panel Discussion
3:10 - 3:20 pm
Break
3:20 - 3:50 pm
Poster Previews
Moderators: Bart Rypma & Charles Guttmann
3:50 - 4:35 pm
Discussion and Workshop Wrap-Up
Moderator: Richard Dortch
4:35 pm
Adjourn